Ctps1 antibody

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August undefined, 2024

WebDec 14, 2024 · Step Pharma announces promising pre-clinical cancer data. Step Pharma has announced encouraging pre-clinical data on its first-in-class, highly selective, orally bioavailable CTPS1 inhibitor, STP938. The data were…. December 12, 2024 - 2 minutes - … http://www.zen-bioscience.com/prod_view.aspx?IsActiveTarget=True&TypeId=163&Id=430165&FId=t3:163:3

Recombinant Human CTP synthase 1(CTPS1) - Cusabio

WebAug 4, 2024 · CTPS1 is involved in de novo synthesis of the CTP nucleotide from uridine triphosphate and glutamine, which is a required precursor for DNA synthesis. It is strongly upregulated in T cells after T-cell receptor activation, and necessary to elicit a normal proliferative response. WebThe intact gene sequence encoding the human CTP synthase 1 (CTPS1) is expressed in the yeast. The resulting protein is fused with the 6xHis-tag to generate the recombinant human CTPS1 protein. Its purity reaches up to 90% measured by SDS-PAGE. On the gel, this recombinant CTPS1 protein migrated to the molecular weight band of about 70 kDa. ponema brainly

Targeting CTP Synthetase 1 to Restore Interferon Induction and ... - PubMed

WebPharos : Target Details - CTPS1 Jump to section: close Descriptive Data Protein Summary Protein Classes IDG Development Level Summary Expression Data Protein Sequence and Structure Related Tools Behavioral Data Approved Drugs Active Ligands Protein-Protein Interactions Nearest Tclin Targets Pathways Predicted Viral Interactions Phenotypic Data WebCTPS1 Antibody (C-13) is a goat polyclonal IgG; 200 µg/ml; epitope mapping at the C-terminus of CTPS1 of human origin; Discontinued polyclonal antibody; more . CTPS1 (C-13) has been discontinued and replaced by CTPS1 (2G7-1D10): sc-293266. QUICK LINKS. Related Products; Product Citations; WebCTPS1 is an asymmetrical homotetramer with only three of its four monomers contributing to the catalytic domain. The substrates required for enzymatic activity are … ponemah school

Impaired lymphocyte function and differentiation in …

CTPS1 CTP synthase 1 - NIH Genetic Testing Registry (GTR) - NCBI

WebDec 15, 2024 · CTPS forms the cytoophidium in various human cancers. (A-F) The signal of anti-CTPS1 antibody on representative cytoophidium-high sections. (G and H) Immunofluorescence with anti-CTPS1 antibody on tissue sections of non-cancerous prostate and colon. Scale bars = 50 µm. (A′-H′) Magnified images of selected areas … WebCTPS1 Antibodies Target Information There are two genes encoding members of a new family of type II integral membrane proteins. Both are ubiquitously expressed, and tissue … shanty town fnWebCTPS1. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. ponemon data breach report 2020

"WebCTPS1 (cytidine triphosphate synthase 1 or CTP synthase 1) catalyzes the conversion of UTP to CTP through ATP-dependent amination (1). Research studies show that … " - Ctps1 antibody

Ctps1 antibody

Recombinant Human CTP synthase 1(CTPS1) - Cusabio

WebAntibody was affinity purified using an epitope specific to CTPS1 immobilized on solid support. The epitope recognized by A304-543A maps to a region between residue 541 to … WebCTPS1 Antibody recognizes endogenous levels of total CTPS1 protein. This antibody does not cross-react with CTPS2 protein. Species …

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WebReferences Antibody type Host Reactivity Conjugate Antigen sequence Epitope Applications Western blot ELISA Immunocytochemistry Immunoprecipitation … WebMay 28, 2014 · CTPS1 expression was found to be low in resting T cells, but rapidly upregulated following TCR activation. These results highlight a key and specific role of …

WebHome; Products. Featured Collections. Recombinant Rabbit Monoclonal Antibodies; IHC/Pathology Antibodies; KO Validated Antibodies; Antibodies. Primary Antibodies WebThis antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 …

WebFor the independent antibodies validation the evaluation is based on comparison of the staining of two (or more) independent antibodies directed towards independent … WebCTPS1. Recognizes endogenous levels of CTPS protein. Alternative Names (click to expand) anti CTPS antibody, anti CTP synthase 1 antibody, anti CTP synthetase 1 antibody, anti UTP--ammonia ligase 1 antibody, orb213802

WebSep 30, 2024 · Selective inhibition of CTPS1 is a promising approach for the treatment of autoimmune and other T cell-driven diseases, but little is known about the mechanisms underlying selective versus non-selective inhibition. Nimbus scientists, in partnership with researchers from the University of Washington and Schrödinger, used cryo-electron ...

WebCtps1 Antibodies ctps1 Antibodies ctps1-b Antibodies ctpsa Antibodies DDBDRAFT_0206047 Antibodies DDBDRAFT_0230162 Antibodies DDB_0206047 Antibodies DDB_0230162 Antibodies wu:fb49e03 Antibodies wu:fe17b03 Antibodies . Did you look for something else? CTNS Antibodies CTNND2 Antibodies ... ponemon institute cost of cyber crimeWebMar 19, 2013 · Only 1/10 RR positive sera had detectable antibodies to IMPHD2 and none had antibodies to CTPS1. Potentially important autoantibody targets identified on protein arrays included Myc-associated zinc finger protein (MAZI) and ankyrin repeat motif. The majority of HCV patients with RR autoantibodies previously received IFN/ribavirin … poneloya beach nicaraguaWebJul 23, 2024 · CTPS1 Antibody (2G7-1D10) is an IgG 2b κ mouse monoclonal CTPS1 antibody (also designated CTPS1 antibody) suitable for the detection of the CTPS1 … pone listen and donateWebCTPS1 (CTP Synthase 1) is a mitochondrial enzyme that catalyzes the conversion of 3-phosphoglycerate to 2-phosphoglycerate in the glycolysis pathway. The gene encoding for CTPS1 is located on chromosome 10 and is composed of 9 exons that generate two alternatively spliced mRNAs. p. one miracle tabWebAug 1, 2024 · In summary, we identified an important diagnostic biomarker for CRC, namely CTPS1, and its importance was validated at the cellular level. These results suggest that … ponemah bog wildlife sanctuaryWebFeb 5, 2024 · De novo synthesis of small-molecule inhibitors of CTPS1 enabled CTP depletion and IFN induction in SARS-CoV-2 infection, thus impeding SARS-CoV-2 replication. Our work uncovers a strategy that a viral pathogen couples immune evasion to metabolic activation to fuel viral replication. ponemah treatment centerWebCTPS1 Antibody (A304-543A) in WB. Detection of human CTPS1 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from 293T cells prepared using … ponemon third party risk